We invent novel optical probes–luminescent nanocrystals and organic fluorophores–as biosensors and single-molecule probes, develop bioconjugation and targeting chemistries, and image live cells with these reagents. We aim to use interesting and unusual new luminescent nanomaterials to address fundamental questions of cell function.
We’re based at the Molecular Foundry at Berkeley Lab.
Our new paper about Phazr, our new near infrared fluorophore that binds to the peptides that form Alzheimer’s plaques, is up in JACS. Nice job, Line, Zeming, and Ruby!
Also check out our new avalanching nanoparticles papers in Nature Photonics and Nature about intrinsic optical bistability and force sensing.